Veterinary Research College of Veterinary Medicine

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New mucosal vaccine prototype provides….

The UF investigators aim to develop a better vaccine for animals and to ultimately develop a vaccine for humans as well.

Great challenges, great minds meet at UFCVM

A new article in the American Journal of Veterinary Research focuses on college achievements.

Clinician receives Dunkin Award for journal…

Dr. Wendy Mandese was honored for having the best original research article on small animal medicine published in the Journal of Small Animal…

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COVID-19 research

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Three common antihistamine medications have been found in preliminary tests to inhibit infection of cells by the coronavirus that causes COVID-19, University of Florida Health researchers say.

Dr. Leah Reznikov, an assistant professor of physiological sciences, is shown in her laboratory with biological scientist Jackson Liao.

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Funding and compliance information of interest to investigators can be found here.

UF Emerging Pathogens Institute and College of Veterinary Medicine researcher Maureen Long helped build a patient surveillance system in Pakistan to track and diagnose mosquito-borne diseases. The project captured outbreaks and laid the groundwork for a countrywide surveillance, detection and reporting system.

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Broad-based strengths, international collaborations

Our veterinary researchers investigate a wide-range of diseases and vaccines that not only impact the lives of our animal companions, but also humans. Several of our programs are distinctive, nationwide and globally. The Center for Environmental and Human toxicology, based in our college, is a leader in aquatic toxicology, with a major strength in nanotoxicology.

The Vulpe-Martyniuk teams' use of CRISPR technology to explore toxicology-related questions is unique.

ScienceDaily

Are our pets leaking information about us.

Pet and animal-related apps are creating cybersecurity risks to their owners, new research has shown.

Trained dogs can sniff out a deadly deer disease

A study has demonstrated that pet dogs could be trained to sniff out chronic wasting disease, a deadly ailment that affects deer. The proof-of-concept investigation suggests detection dogs could be…

Madagascar mouse lemur retroviruses are diverse and surprisingly similar to ones found in polar bears or domestic sheep

Madagascar is home to a unique biodiversity with a large number of endemic species, among those many lemur species, including the mouse lemurs. This diversity is also found in their…

Atopic dermatitis in dogs linked to certain parts of the genome

Using new gene mapping methods, researchers have found connections between atopic dermatitis (eczema) in dogs and several regions of the genome. Some of the genes identified coincide with genes linked…

Animal Airwaves

A storm is brewing: how natural disasters put pets at increased risk of infectious disease.

Extreme Weather Patterns and Natural Disasters are happening more frequently than ever before, and in addition to the risk they pose for people and property, they also increase the likelihood…

Risk of Raw Food Diets (Archive from May 6, 2022)

So called “raw food diets” may mean different things to different people, but pet owners need to understand the risks associated with feeding diets other than pet food manufactured commercially….

Managing Care of Elderly Pets (Archive from Aug. 6, 2021)

Similar to people, pets are living longer lives these days due to improved veterinary care and dietary habits. But with extended lives comes a whole new set of age-related conditions,…

Veterinary Disaster Response: A Crucial Function

In the aftermath of a disaster, veterinary colleges are often called upon to respond, whether by sending teams into the field to provide direct medical assistance to injured or displaced…

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The effect of O-antigen length determinant wzz on the immunogenicity of Salmonella Typhimurium for Escherichia coli O2 O-polysaccharides delivery

Attenuated Salmonella Typhimurium is a promising antigen delivery system for live vaccines such as polysaccharides. The length of polysaccharides is a well-known key factor in modulating the immune response induc...

Insights on the effects of antimicrobial and heavy metal usage on the antimicrobial resistance profiles of pigs based on culture-independent studies

Antimicrobial resistance is a global threat to human, animal, and environmental health. In pig production, antimicrobials and heavy metals such as zinc oxide are commonly used for treatment and prevention of d...

Bacterial chondronecrosis with osteomyelitis related Enterococcus cecorum isolates are genetically distinct from the commensal population and are more virulent in an embryo mortality model

Bacterial chondronecrosis with osteomyelitis (BCO) is a common cause of broiler lameness. Bacteria that are found in BCO lesions are intestinal bacteria that are proposed to have translocated through the intes...

Temporal transcriptome profiling of floating apical out chicken enteroids suggest stability and reproducibility

Enteroids are miniature self-organising three-dimensional (3D) tissue cultures which replicate much of the complexity of the intestinal epithelium. We recently developed an apical-out leukocyte-containing chic...

Using random forest to predict antimicrobial minimum inhibitory concentrations of nontyphoidal Salmonella in Taiwan

Antimicrobial resistance (AMR) is a global health issue and surveillance of AMR can be useful for understanding AMR trends and planning intervention strategies. Salmonella , widely distributed in food-producing an...

A molecular epidemiological study on Escherichia coli in young chicks with colibacillosis identified two possible outbreaks across farms

Avian pathogenic Escherichia coli (APEC) is the cause of colibacillosis outbreaks in young poultry chicks, resulting in acute to peracute death. The high morbidity and mortality caused by colibacillosis results i...

Porcine epidemic diarrhea virus activates PERK-ROS axis to benefit its replication in Vero E6 cells

Of the three branches of unfolded protein response (UPR) that were reportedly activated by porcine epidemic diarrhea virus (PEDV), PERK is recently shown to act as an upstream regulator of oxidative response o...

Review on the methodology to assess respiratory tract lesions in pigs and their production impact

Porcine respiratory disease is one of the most important health problems in pig production worldwide. Cranioventral pulmonary consolidation (CVPC) and pleurisy are the two most common lesions in the respirator...

Vimentin affects inflammation and neutrophil recruitment in airway epithelium during Streptococcus suis serotype 2 infection

Streptococcus suis serotype 2 (SS2) frequently colonizes the swine upper respiratory tract and can cause Streptococcal disease in swine with clinical manifestations of pneumonia, meningitis, and septicemia. Previ...

Effector protein Hcp2a of avian pathogenic Escherichia coli interacts with the endoplasmatic reticulum associated RPL23 protein of chicken DF-1 fibroblasts

The type VI secretion system (T6SS) is a secretion apparatus widely found in pathogenic Gram-negative bacteria and is important for competition among various bacteria and host cell pathogenesis. Hcp is a core ...

DHAV 3CD targets IRF7 and RIG-I proteins to block the type I interferon upstream signaling pathway

Duck hepatitis A virus type 1 (DHAV-1) is an acute, highly lethal infectious agent that infects ducklings and causes up to 95% mortality in ducklings up to 1 week of age, posing a significant economic threat t...

Infectivity and transmissibility of an avian H3N1 influenza virus in pigs

In 2019 a low pathogenic H3N1 avian influenza virus (AIV) caused an outbreak in Belgian poultry farms, characterized by an unusually high mortality in chickens. Influenza A viruses of the H1 and H3 subtype can...

In-depth health surveillance and clinical nutrition in farmed Atlantic salmon: a strategic attempt to detect and mitigate an HSMI outbreak

Fish health personnel have limited tools in combatting viral diseases such as heart and skeletal muscle inflammation (HSMI) in open net-pen farmed Atlantic salmon. In this study, we aimed to predict HSMI by in...

Fasciola hepatica primoinfections and reinfections in sheep drive distinct Th1/Th2/Treg immune responses in liver and hepatic lymph node at early and late stages

The expression of proinflammatory (IL-1β, IFN-γ, TNF-α) and regulatory (IL-10, TGF-β, IL-4) cytokines, as well as the transcription factor FoxP3, was quantified in the liver and hepatic lymph node (HLN) of she...

Laminin-binding protein of Streptococcus suis serotype 2 influences zinc acquisition and cytokine responses

Streptococcus suis serotype 2 is an important bacterial pathogen of swine, responsible for substantial economic losses to the swine industry worldwide. The knowledge on the pathogenesis of the infection caused by...

Hemolysin function of Listeria is related to biofilm formation: transcriptomics analysis

Listeriolysin O (LLO) is the main virulence protein of Listeria monocytogenes (LM), that helps LM escape lysosomes. We previously found that the cellular immune response elicited by L.ivanovii (LI) is weaker than...

Correction: HA gene amino acid mutations contribute to antigenic variation and immune escape of H9N2 influenza virus

The original article was published in Veterinary Research 2022 53 :43

Second passage experiments of chronic wasting disease in transgenic mice overexpressing human prion protein

Chronic wasting disease (CWD) is a prion disease of cervids including deer, elk, reindeer, and moose. Human consumption of cervids is common, therefore assessing the risk potential of CWD transmission to human...

Influence of heat stress on intestinal integrity and the caecal microbiota during Enterococcus cecorum infection in broilers

Enterococcus cecorum (EC) is one of the most relevant bacterial pathogens in modern broiler chicken production from an economic and animal welfare perspective. Although EC pathogenesis is generally well described...

Transcriptomic analysis of spleen B cell revealed the molecular basis of bursopentin on B cell differentiation

The bursa of Fabricius, the acknowledged humoral immune organ unique to birds, plays a vital role in B cell development. Bursopentin (BP5) derived from the bursa is reported to induce the development and forma...

Pathogenicity of highly pathogenic avian influenza H5N8 subtype for herring gulls ( Larus argentatus ): impact of homo- and heterosubtypic immunity on the outcome of infection

To improve understanding of the pathobiology of highly pathogenic avian influenza virus (HPAIV) infections in wild birds, pathogenicity and transmissibility of HPAIV H5N8 subtype clade 2.3.4.4b was evaluated i...

Evaluating the potential of whole-genome sequencing for tracing transmission routes in experimental infections and natural outbreaks of bovine respiratory syncytial virus

Bovine respiratory syncytial virus (BRSV) is a major cause of respiratory disease in cattle. Genomic sequencing can resolve phylogenetic relationships between virus populations, which can be used to infer tran...

Understanding the incidence and timing of rabies cases in domestic animals and wildlife in south-east Tanzania in the presence of widespread domestic dog vaccination campaigns

The “Zero by 30” strategic plan aims to eliminate human deaths from dog-mediated rabies by 2030 and domestic dog vaccination is a vital component of this strategic plan. In areas where domestic dog vaccination...

Erysipelothrix rhusiopathiae -specific T-cell responses after experimental infection of chickens selectively bred for high and low serum levels of mannose-binding lectin

Erysipelas, caused by infection with Erysipelothrix rhusiopathiae (ER) is an important emerging disease in laying hens. We have earlier observed prominent mannose-binding lectin (MBL) acute phase responses in exp...

DAD3 targets ACE2 to inhibit the MAPK and NF-κB signalling pathways and protect against LPS-induced inflammation in bovine mammary epithelial cells

The protective arm of the renin-angiotensin system (RAS), the ACE 2/Ang-(1–7)/MasR axis, has become a new anti-inflammatory target. As a specific activator of ACE2, diminazene aceturate (DA) can promote anti-i...

Mycoplasma gallisepticum escapes the host immune response via gga-miR-365-3p/SOCS5/STATs axis

A disruption in the expression of gga-miR-365-3p was confirmed in the Mycoplasma gallisepticum (MG)-infected Chicken primary alveolar type II epithelial (CP-II) cells based on previous sequencing results, but the...

research topics veterinary

Learning and strategic imitation in modelling farmers’ dynamic decisions on bovine viral diarrhoea vaccination

Considering human decision-making is essential for understanding the mechanisms underlying the propagation of real-life diseases. We present an extension of a model for pathogen spread that considers farmers’ ...

Systematic identification and characterization of repeat sequences in African swine fever virus genomes

African swine fever virus (ASFV) is a large DNA virus that infects domestic pigs with high morbidity and mortality rates. Repeat sequences, which are DNA sequence elements that are repeated more than twice in ...

Chicken telomerase reverse transcriptase promotes the tumorigenicity of avian leukosis virus subgroup J by regulating the Wnt/β-catenin signaling pathway

This research aimed to analyze the regulatory effect of chicken telomerase reverse transcriptase (chTERT) on the Wnt/β-catenin signaling pathway and its effect on the tumorigenicity of avian leukosis virus sub...

Current situation and future direction of Newcastle disease vaccines

Newcastle disease (ND) is one of the most economically devastating infectious diseases affecting the poultry industry. Virulent Newcastle disease virus (NDV) can cause high mortality and severe tissue lesions ...

Anti-inflammatory effects of the prostaglandin D 2 /prostaglandin DP1 receptor and lipocalin-type prostaglandin D 2 synthase/prostaglandin D 2 pathways in bacteria-induced bovine endometrial tissue

Dairy cows often develop different degrees of endometritis after calving and this is attributed to pathogenic bacterial infections such as by Escherichia coli and Staphylococcus aureus . Infection of the bovine en...

KbvR mutant of Klebsiella pneumoniae affects the synthesis of type 1 fimbriae and provides protection to mice as a live attenuated vaccine

Klebsiella pneumoniae is a leading cause of severe infections in humans and animals, and the emergence of multidrug-resistant strains highlights the need to develop effective vaccines for preventing such infecti...

Screening of colistin-resistant bacteria in livestock animals from France

Colistin is frequently used as a growth factor or treatment against infectious bacterial diseases in animals. The Veterinary Division of the European Medicines Agency (EMA) restricted colistin use as a second-...

Genotyping and biofilm formation of Mycoplasma hyopneumoniae and their association with virulence

Mycoplasma hyopneumoniae , the causative agent of swine respiratory disease, demonstrates differences in virulence. However, factors associated with this variation remain unknown. We herein evaluated the associati...

Sex—the most underappreciated variable in research: insights from helminth-infected hosts

The sex of a host affects the intensity, prevalence, and severity of helminth infection. In many cases, one sex has been found to be more susceptible than the other, with the prevalence and intensity of helmin...

Regulation of alphaherpesvirus protein via post-translational phosphorylation

An alphaherpesvirus carries dozens of viral proteins in the envelope, tegument and capsid structure, and each protein plays an indispensable role in virus adsorption, invasion, uncoating and release. After inf...

Multi-locus sequence analysis reveals great genetic diversity among Mycoplasma capricolum subsp. capripneumoniae strains in Asia

Multi-Locus Sequence Analysis (MLSA) of Mycoplasma capricolum subsp. capripneumoniae ( Mccp ) strains from Asia revealed unforeseen diversity and a central position for genotyping groups representing strains from C...

How Streptococcus suis escapes antibiotic treatments

Streptococcus suis is a zoonotic agent that causes sepsis and meningitis in pigs and humans. S. suis infections are responsible for large economic losses in pig production. The lack of effective vaccines to preve...

FABP4-mediated lipid droplet formation in Streptococcus uberis -infected macrophages supports host defence

Foamy macrophages containing prominent cytoplasmic lipid droplets (LDs) are found in a variety of infectious diseases. However, their role in Streptococcus uberis -induced mastitis is unknown. Herein, we report th...

Long noncoding RNA IRF1-AS is associated with peste des petits ruminants infection

Peste des petits ruminants (PPR) is an acute and highly contagious disease and has long been a significant threat to small ruminant productivity worldwide. However, the molecular mechanism underlying host-PPRV...

Heat-labile enterotoxin enhances F4-producing enterotoxigenic E. coli adhesion to porcine intestinal epithelial cells by upregulating bacterial adhesins and STb enterotoxin

As one of the crucial enterotoxins secreted by enterotoxigenic Escherichia coli (ETEC), heat-labile enterotoxin (LT) enhances bacterial adherence both in vivo and in vitro; however, the underlying mechanism remai...

Effects of exosomes derived from Trichinella spiralis infective larvae on intestinal epithelial barrier function

Muscle larvae of Trichinella spiralis parasitize the host intestinal epithelium. The mechanisms of exosomes participating in the invasion of T. spiralis muscle larvae are unclear. Hence, the purpose of this study...

Risk of transmission of foot-and-mouth disease by wild animals: infection dynamics in Japanese wild boar following direct inoculation or contact exposure

Understanding of disease dynamics and viral shedding in wild boar and of the potential for disease spreading within wild boar and domestic pig populations is critical for developing effective control and eradi...

A novel C-type lectin from Trichinella spiralis mediates larval invasion of host intestinal epithelial cells

The aim of this study was to investigate the characteristics of a novel type C lectin from Trichinella spiralis (TsCTL) and its role in larval invasion of intestinal epithelial cells (IECs). TsCTL has a carbohydr...

Species identification by MALDI-TOF MS and gap PCR–RFLP of non- aureus Staphylococcus , Mammaliicoccus , and Streptococcus spp. associated with sheep and goat mastitis

Staphylococci and streptococci are common causes of intramammary infection in small ruminants, and reliable species identification is crucial for understanding epidemiology and impact on animal health and welf...

Baicalin acts as an adjuvant to potentiate the activity of azithromycin against Staphylococcus saprophyticus biofilm: an in vitro, in vivo, and molecular study

Staphylococcus saprophyticus is frequently involved in various difficult-to-treat infections due to the formation of biofilms. To identify useful antibiofilm strategies, this study explored the efficacy and mecha...

Chicken miR-126-5p negatively regulates antiviral innate immunity by targeting TRAF3

Innate immunity plays an essential role in preventing the invasion of pathogenic microorganisms. However, innate immunity is a double-edged sword, whose excessive activation is detrimental to immune homeostasi...

The important role of NLRP6 inflammasome in Pasteurella multocida infection

Pasteurella multocida ( P. multocida ) can cause severe respiratory disease in cattle, resulting in high mortality and morbidity. Inflammasomes are multiprotein complexes in the cytoplasm that recognize pathogens a...

Genomic characterization of peste des petits ruminants vaccine seed “45G37/35-k”, Russia

Production of peste des petits ruminants (PPR) vaccines in Russia is based on two attenuated virus strains (“45G37/35-k” and “ARRIAH”) of common origin. Here, the identity of the strain PPRV/45G37/35-k was inv...

Molecular detection of Helicobacter spp. and Fusobacterium gastrosuis in pigs and wild boars and its association with gastric histopathological alterations

Besides Helicobacter pylori , a Gram-negative bacterium that may cause gastric disorders in humans, non- Helicobacter pylori helicobacters (NHPH) may also colonize the stomach of humans and animals. In pigs, H. sui...

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244 Awesome Animal Topics for Research Papers

animal topics for research papers

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  1. Veterinary Research » College of Veterinary Medicine

    Our veterinary researchers investigate a wide-range of diseases and vaccines that not only impact the lives of our animal companions, but also humans. Several of our programs are distinctive, nationwide and globally. The Center for Environmental and Human toxicology, based in our college, is a leader in aquatic toxicology, with a major strength ...

  2. Veterinary Research

    In-depth health surveillance and clinical nutrition in farmed Atlantic salmon: a strategic attempt to detect and mitigate an HSMI outbreak. Fish health personnel have limited tools in combatting viral diseases such as heart and skeletal muscle inflammation (HSMI) in open net-pen farmed Atlantic salmon.

  3. Small Animal Topics

    Bone Tumors in Cats and Dogs Bowel Obstruction Boxer Ear Brachycephalic Syndrome Breast Cancer Broken Bone Broken Jaw Bronchoalveolar Carcinoma Bronchogenic Carcinoma Bulla Osteotomy Bullae C-Kit Mutation C1-C2 Luxation Calcaneal Tendon Injuries Cancer Canine Elbow Dysplasia Canine Hip Dysplasia Cartilage Chip Castration Caudal Hernia

  4. Animal Health Topics

    The American College of Veterinary Surgeons is the agency by which veterinarians are certified as specialists in surgery. The mission of ACVS is to advance the art and science of surgery and promote excellence in animal health care through research, education and service to the public.

  5. 244 Free Animal Topics for Research Papers

    Here are some great ideas for you: Cats make the best pets Animals should not be held in captivity Exotic pet ownership must be banned Palm oil should be banned Zoos should be more tightly regulated Never feed wildlife no matter what We need more elephant sanctuaries Stopping Maasai from hunting ...